miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell Maturation

Renal tubular injury and innate immune responses induced by hypoxia contribute to acute kidney injury. Accumulating evidence suggests that miR-21 overexpression protects against kidney ischemia injury. Additionally, miR-21 emerges as a key inhibitor in dendritic cell maturation. Thus, we hypothesize...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Song, Nana, Zhang, Ting, Xu, XiaLian, Lu, Zhihui, Yu, Xiaofang, Fang, Yi, Hu, Jiachang, Jia, Ping, Teng, Jie, Ding, Xiaoqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036242/
https://ncbi.nlm.nih.gov/pubmed/30013485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00790
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