Presence of Cytotoxic Extracellular Histones in Machine Perfusate of Donation After Circulatory Death Kidneys

BACKGROUND: Extracellular histones are cytotoxic molecules that are related to cell stress and death. They have been shown to play a crucial role in multiple pathophysiologic processes like sepsis, inflammation, vascular dysfunction, and thrombosis. Their role in organ donation and graft function an...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Transplantation
Main Authors: van Smaalen, Tim C., Beurskens, Daniëlle M. H., Hoogland, E. R. Pieter, Winkens, Bjorn, Christiaans, Maarten H. L., Reutelingsperger, Chris P., van Heurn, L. W. Ernest, Nicolaes, Gerry A. F.
Format: Artigo
Jezik:Inglês
Izdano: Wolters Kluwer 2017
Teme:
Original Basic Science—General
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228581/
https://ncbi.nlm.nih.gov/pubmed/27906828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001590
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