Harnessing the immune system via FcγR function in immune therapy: a pathway to next‐gen mAbs

The human fragment crystallizable (Fc)γ receptor (R) interacts with antigen‐complexed immunoglobulin (Ig)G ligands to both activate and modulate a powerful network of inflammatory host‐protective effector functions that are key to the normal physiology of immune resistance to pathogens. More than 10...

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Библиографические подробности
Опубликовано в: :Immunol Cell Biol
Главные авторы: Chenoweth, Alicia M, Wines, Bruce D, Anania, Jessica C, Mark Hogarth, P
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
SPECIAL FEATURE: Multifaceted roles of antibody Fc effector functions: from protection to pathology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228307/
https://ncbi.nlm.nih.gov/pubmed/32157732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12326
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