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Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice
BACKGROUND: Fractalkine (CX3CL1; FKN) is a chemokine expressed by neurons that mediates communication between neurons and microglia. By regulating microglial activity, CX3CL1 can mitigate the damaging effects of chronic microglial inflammation within the brain, a state that plays a major role in agi...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Neuroinflammation |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7227354/ https://ncbi.nlm.nih.gov/pubmed/32410624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01828-y |
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