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Interleukin 26 Skews Macrophage Polarization Towards M1 Phenotype by Activating cJUN and the NF-κB Pathway

Interleukin 26 (IL-26) is a new member of the IL-10 family that is highly expressed in rheumatoid arthritis (RA). However, the functions of IL-26 produced by macrophages in RA have not been elucidated. In the present work, we evaluated the effects and the mechanisms of IL-26 on M1 and M2 macrophage...

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Publicat a:Cells
Autors principals: Lin, Yi-Hsuan, Wang, Yi-Hsun, Peng, Yi-Jen, Liu, Feng-Cheng, Lin, Gu-Jiun, Huang, Shing-Hwa, Sytwu, Huey-Kang, Cheng, Chia-Pi
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227026/
https://ncbi.nlm.nih.gov/pubmed/32290250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040938
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