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Electro-Osmotic Vortices Promote the Capture of Folded Proteins by PlyAB Nanopores

[Image: see text] Biological nanopores are emerging as powerful tools for single-molecule analysis and sequencing. Here, we engineered the two-component pleurotolysin (PlyAB) toxin to assemble into 7.2 × 10.5 nm cylindrical nanopores with a low level of electrical noise in lipid bilayers, and we add...

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Detalhes bibliográficos
Publicado no:Nano Lett
Main Authors: Huang, Gang, Willems, Kherim, Bartelds, Mart, van Dorpe, Pol, Soskine, Misha, Maglia, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227020/
https://ncbi.nlm.nih.gov/pubmed/32271587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.0c00877
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