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Electro-osmotic capture and ionic discrimination of peptide and protein biomarkers with FraC nanopores

Biological nanopores are nanoscale sensors employed for high-throughput, low-cost, and long read-length DNA sequencing applications. The analysis and sequencing of proteins, however, is complicated by their folded structure and non-uniform charge. Here we show that an electro-osmotic flow through Fr...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Huang, Gang, Willems, Kherim, Soskine, Misha, Wloka, Carsten, Maglia, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715100/
https://ncbi.nlm.nih.gov/pubmed/29038539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01006-4
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