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Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone Model

To unravel the failure of remyelination in multiple sclerosis (MS) and to test promising remyelinating treatments, suitable animal models like the well-established cuprizone model are required. However, this model is only standardized in young mice. This does not represent the typical age of MS pati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cells
Egile Nagusiak: Gingele, Stefan, Henkel, Florian, Heckers, Sandra, Moellenkamp, Thiemo M., Hümmert, Martin W., Skripuletz, Thomas, Stangel, Martin, Gudi, Viktoria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226973/
https://ncbi.nlm.nih.gov/pubmed/32290524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040945
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