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Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone Model

To unravel the failure of remyelination in multiple sclerosis (MS) and to test promising remyelinating treatments, suitable animal models like the well-established cuprizone model are required. However, this model is only standardized in young mice. This does not represent the typical age of MS pati...

詳細記述

保存先:
書誌詳細
出版年:Cells
主要な著者: Gingele, Stefan, Henkel, Florian, Heckers, Sandra, Moellenkamp, Thiemo M., Hümmert, Martin W., Skripuletz, Thomas, Stangel, Martin, Gudi, Viktoria
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226973/
https://ncbi.nlm.nih.gov/pubmed/32290524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040945
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