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Redox regulation of tumor suppressor PTEN in cell signaling
Phosphatase and tensin homologs deleted on chromosome 10 (PTEN) is a potent tumor suppressor and often dysregulated in cancers. Cellular PTEN activity is restrained by the oxidation of active-site cysteine by reactive oxygen species (ROS). Recovery of its enzymatic activity predominantly depends on...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Redox Biol |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7226887/ https://ncbi.nlm.nih.gov/pubmed/32413744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101553 |
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