Proton Irradiation Increases the Necessity for Homologous Recombination Repair Along with the Indispensability of Non-Homologous End Joining

Technical improvements in clinical radiotherapy for maximizing cytotoxicity to the tumor while limiting negative impact on co-irradiated healthy tissues include the increasing use of particle therapy (e.g., proton therapy) worldwide. Yet potential differences in the biology of DNA damage induction a...

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Publicado no:Cells
Main Authors: Szymonowicz, Klaudia, Krysztofiak, Adam, van der Linden, Jansje, Kern, Ajvar, Deycmar, Simon, Oeck, Sebastian, Squire, Anthony, Koska, Benjamin, Hlouschek, Julian, Vüllings, Melanie, Neander, Christian, Siveke, Jens T., Matschke, Johann, Pruschy, Martin, Timmermann, Beate, Jendrossek, Verena
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226794/
https://ncbi.nlm.nih.gov/pubmed/32260562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040889
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