Proton Irradiation Increases the Necessity for Homologous Recombination Repair Along with the Indispensability of Non-Homologous End Joining

Technical improvements in clinical radiotherapy for maximizing cytotoxicity to the tumor while limiting negative impact on co-irradiated healthy tissues include the increasing use of particle therapy (e.g., proton therapy) worldwide. Yet potential differences in the biology of DNA damage induction a...

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Publicat a:Cells
Autors principals: Szymonowicz, Klaudia, Krysztofiak, Adam, van der Linden, Jansje, Kern, Ajvar, Deycmar, Simon, Oeck, Sebastian, Squire, Anthony, Koska, Benjamin, Hlouschek, Julian, Vüllings, Melanie, Neander, Christian, Siveke, Jens T., Matschke, Johann, Pruschy, Martin, Timmermann, Beate, Jendrossek, Verena
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226794/
https://ncbi.nlm.nih.gov/pubmed/32260562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040889
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