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Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons

Proton beam therapy is increasingly applied for the treatment of human cancer, as it promises to reduce normal tissue damage. However, little is known about the relationship between linear energy transfer (LET), the type of DNA damage, and cellular repair mechanisms, particularly for cells irradiate...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Oeck, Sebastian, Szymonowicz, Klaudia, Wiel, Gesa, Krysztofiak, Adam, Lambert, Jamil, Koska, Benjamin, Iliakis, George, Timmermann, Beate, Jendrossek, Verena
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320817/
https://ncbi.nlm.nih.gov/pubmed/30486506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123779
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