Directed Differentiation of Mobilized Hematopoietic Stem and Progenitor Cells into Functional NK Cells with Enhanced Antitumor Activity

Obtaining sufficient numbers of functional natural killer (NK) cells is crucial for the success of NK-cell-based adoptive immunotherapies. While expansion from peripheral blood (PB) is the current method of choice, ex vivo generation of NK cells from hematopoietic stem and progenitor cells (HSCs) ma...

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Pubblicato in:Cells
Autori principali: Oberoi, Pranav, Kamenjarin, Kathrina, Villena Ossa, Jose Francisco, Uherek, Barbara, Bönig, Halvard, Wels, Winfried S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226771/
https://ncbi.nlm.nih.gov/pubmed/32230942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040811
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