Directed Differentiation of Mobilized Hematopoietic Stem and Progenitor Cells into Functional NK Cells with Enhanced Antitumor Activity

Obtaining sufficient numbers of functional natural killer (NK) cells is crucial for the success of NK-cell-based adoptive immunotherapies. While expansion from peripheral blood (PB) is the current method of choice, ex vivo generation of NK cells from hematopoietic stem and progenitor cells (HSCs) ma...

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Опубликовано в: :Cells
Главные авторы: Oberoi, Pranav, Kamenjarin, Kathrina, Villena Ossa, Jose Francisco, Uherek, Barbara, Bönig, Halvard, Wels, Winfried S.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226771/
https://ncbi.nlm.nih.gov/pubmed/32230942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040811
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