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Chimeric Antigen Receptor Cell Therapy: Overcoming Obstacles to Battle Cancer
Chimeric antigen receptors (CAR) are fusion proteins engineered from antigen recognition, signaling, and costimulatory domains that can be used to reprogram T cells to specifically target tumor cells expressing specific antigens. Current CAR-T cell technology utilizes the patient’s own T cells to st...
Gespeichert in:
| Veröffentlicht in: | Cancers (Basel) |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7226583/ https://ncbi.nlm.nih.gov/pubmed/32244520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040842 |
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