Differentially Methylated Ultra-Conserved Regions Uc160 and Uc283 in Adenomas and Adenocarcinomas Are Associated with Overall Survival of Colorectal Cancer Patients

Deregulation of the transcribed ultra-conserved regions (T-UCRs) Uc160, Uc283, and Uc346 has been reported in colorectal cancer (CRC) recently. Here, we investigated promoter methylation of these T-UCRs during the adenoma–carcinoma sequence and their clinical significance in CRC patients. Methylatio...

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Publicat a:Cancers (Basel)
Autors principals: Kottorou, Anastasia E., Dimitrakopoulos, Foteinos-Ioannis D., Antonacopoulou, Anna G., Diamantopoulou, Georgia, Tsoumas, Dimitrios, Koutras, Angelos, Makatsoris, Thomas, Stavropoulos, Michalis, Thomopoulos, Konstantinos C., Hulbert, Alicia, Tzelepi, Vassiliki, Kalofonos, Haralabos P.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226527/
https://ncbi.nlm.nih.gov/pubmed/32272654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040895
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