Deregulation of methylation of transcribed-ultra conserved regions in colorectal cancer and their value for detection of adenomas and adenocarcinomas

Expression of Transcribed Ultraconserved Regions (T-UCRs) is often deregulated in cancer. The present study assesses the expression and methylation of three T-UCRs (Uc160, Uc283 and Uc346) in colorectal cancer (CRC) and explores the potential of T-UCR methylation in circulating DNA for the detection...

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Publicat a:Oncotarget
Autors principals: Kottorou, Anastasia E., Antonacopoulou, Anna G., Dimitrakopoulos, Foteinos-Ioannis D., Diamantopoulou, Georgia, Sirinian, Chaido, Kalofonou, Melpomeni, Theodorakopoulos, Theodoros, Oikonomou, Chrysa, Katsakoulis, Evangelos C., Koutras, Angelos, Makatsoris, Thomas, Demopoulos, Nikos, Stephanou, Georgia, Stavropoulos, Michalis, Thomopoulos, Konstantinos C., Kalofonos, Haralabos P.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940382/
https://ncbi.nlm.nih.gov/pubmed/29765549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25115
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