Deregulation of methylation of transcribed-ultra conserved regions in colorectal cancer and their value for detection of adenomas and adenocarcinomas

Expression of Transcribed Ultraconserved Regions (T-UCRs) is often deregulated in cancer. The present study assesses the expression and methylation of three T-UCRs (Uc160, Uc283 and Uc346) in colorectal cancer (CRC) and explores the potential of T-UCR methylation in circulating DNA for the detection...

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Wydane w:Oncotarget
Główni autorzy: Kottorou, Anastasia E., Antonacopoulou, Anna G., Dimitrakopoulos, Foteinos-Ioannis D., Diamantopoulou, Georgia, Sirinian, Chaido, Kalofonou, Melpomeni, Theodorakopoulos, Theodoros, Oikonomou, Chrysa, Katsakoulis, Evangelos C., Koutras, Angelos, Makatsoris, Thomas, Demopoulos, Nikos, Stephanou, Georgia, Stavropoulos, Michalis, Thomopoulos, Konstantinos C., Kalofonos, Haralabos P.
Format: Artigo
Język:Inglês
Wydane: Impact Journals LLC 2018
Hasła przedmiotowe:
Research Paper
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940382/
https://ncbi.nlm.nih.gov/pubmed/29765549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25115
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