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Therapeutic Strategies and Biomarkers to Modulate PARP Activity for Targeted Cancer Therapy

Poly-(ADP-ribose) polymerase 1 (PARP1) is commonly known for its vital role in DNA damage response and repair. However, its enzymatic activity has been linked to a plethora of physiological and pathophysiological transactions ranging from cellular proliferation, survival and death. For instance, mal...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Singh, Naveen, Pay, S. Louise, Bhandare, Snehal B., Arimpur, Udhaya, Motea, Edward A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226473/
https://ncbi.nlm.nih.gov/pubmed/32295316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040972
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