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Potent Anticancer Effect of the Natural Steroidal Saponin Gracillin Is Produced by Inhibiting Glycolysis and Oxidative Phosphorylation-Mediated Bioenergetics

Metabolic rewiring to utilize aerobic glycolysis is a hallmark of cancer. However, recent findings suggest the role of mitochondria in energy generation in cancer cells and the metabolic switch to oxidative phosphorylation (OXPHOS) in response to the blockade of glycolysis. We previously demonstrate...

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Bibliografski detalji
Izdano u:Cancers (Basel)
Glavni autori: Min, Hye-Young, Pei, Honglan, Hyun, Seung Yeob, Boo, Hye-Jin, Jang, Hyun-Ji, Cho, Jaebeom, Kim, Ji Hye, Son, Jaekyoung, Lee, Ho-Young
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226187/
https://ncbi.nlm.nih.gov/pubmed/32276500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040913
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