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The Cytosolic Phospholipase A(2)α N-Terminal C2 Domain Binds and Oligomerizes on Membranes with Positive Curvature
Group IV phospholipase A(2)α (cPLA(2)α) regulates the production of prostaglandins and leukotrienes via the formation of arachidonic acid from membrane phospholipids. The targeting and membrane binding of cPLA(2)α to the Golgi involves the N-terminal C2 domain, whereas the catalytic domain produces...
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| Publié dans: | Biomolecules |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7226022/ https://ncbi.nlm.nih.gov/pubmed/32331436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10040647 |
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