Lack of PCSK6 Increases Flow-Mediated Outward Arterial Remodeling in Mice

Proprotein convertases (PCSKs) process matrix metalloproteases and cytokines, but their function in the vasculature is largely unknown. Previously, we demonstrated upregulation of PCSK6 in atherosclerotic plaques from symptomatic patients, localization to smooth muscle cells (SMCs) in the fibrous ca...

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Pubblicato in:Cells
Autori principali: Röhl, Samuel, Suur, Bianca E., Lengquist, Mariette, Seime, Till, Caidahl, Kenneth, Hedin, Ulf, Arner, Anders, Matic, Ljubica, Razuvaev, Anton
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225991/
https://ncbi.nlm.nih.gov/pubmed/32325687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9041009
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