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Pangolins Lack IFIH1/MDA5, a Cytoplasmic RNA Sensor That Initiates Innate Immune Defense Upon Coronavirus Infection

Zoonotic infections are an imminent threat to human health. Pangolins were recently identified as carriers and intermediate hosts of coronaviruses. Previous research has shown that infection with coronaviruses activates an innate immune response upon sensing of viral RNA by interferon-induced with h...

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Foilsithe in:Front Immunol
Main Authors: Fischer, Heinz, Tschachler, Erwin, Eckhart, Leopold
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225364/
https://ncbi.nlm.nih.gov/pubmed/32574256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00939
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