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The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?

Thyrotropin releasing hormone (TRH: Glp-His-Pro-NH(2)) is a peptide mainly produced by brain neurons. In mammals, hypophysiotropic TRH neurons of the paraventricular nucleus of the hypothalamus integrate metabolic information and drive the secretion of thyrotropin from the anterior pituitary, and th...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Charli, Jean-Louis, Rodríguez-Rodríguez, Adair, Hernández-Ortega, Karina, Cote-Vélez, Antonieta, Uribe, Rosa María, Jaimes-Hoy, Lorraine, Joseph-Bravo, Patricia
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225337/
https://ncbi.nlm.nih.gov/pubmed/32457627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00640
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