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Identification of the thyrotropin-releasing-hormone-degrading ectoenzyme as a metallopeptidase.

A time-dependent inhibition of the thyrotropin-releasing-hormone (TRH)-degrading ectoenzyme (EC 3.4.19.-) from rat brain by the metal-complexing agents imidazole, NaCN, EDTA and 1,10-phenanthroline could be demonstrated. In contrast, the inhibition by the non-chelating analogues 4,7- and 1,7-phenant...

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Detalhes bibliográficos
Main Authors: Czekay, G, Bauer, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132368/
https://ncbi.nlm.nih.gov/pubmed/8096131
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