Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation

During Drosophila and vertebrate brain development, the conserved transcription factor Prospero/Prox1 is an important regulator of the transition between proliferation and differentiation. Prospero level is low in neural stem cells and their immediate progeny, but is upregulated in larval neurons an...

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Bibliographic Details
Published in:Biol Open
Main Authors: Samuels, Tamsin J., Arava, Yoav, Järvelin, Aino I., Robertson, Francesca, Lee, Jeffrey Y., Yang, Lu, Yang, Ching-Po, Lee, Tzumin, Ish-Horowicz, David, Davis, Ilan
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225087/
https://ncbi.nlm.nih.gov/pubmed/32205310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.049684
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