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Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation

During Drosophila and vertebrate brain development, the conserved transcription factor Prospero/Prox1 is an important regulator of the transition between proliferation and differentiation. Prospero level is low in neural stem cells and their immediate progeny, but is upregulated in larval neurons an...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Samuels, Tamsin J., Arava, Yoav, Järvelin, Aino I., Robertson, Francesca, Lee, Jeffrey Y., Yang, Lu, Yang, Ching-Po, Lee, Tzumin, Ish-Horowicz, David, Davis, Ilan
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225087/
https://ncbi.nlm.nih.gov/pubmed/32205310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.049684
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