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Robustness and parameter geography in post-translational modification systems

Biological systems are acknowledged to be robust to perturbations but a rigorous understanding of this has been elusive. In a mathematical model, perturbations often exert their effect through parameters, so sizes and shapes of parametric regions offer an integrated global estimate of robustness. He...

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Publicat a:PLoS Comput Biol
Autors principals: Nam, Kee-Myoung, Gyori, Benjamin M., Amethyst, Silviana V., Bates, Daniel J., Gunawardena, Jeremy
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224580/
https://ncbi.nlm.nih.gov/pubmed/32365103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007573
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