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Chemoenzymatic platform for synthesis of chiral organofluorines based on type II aldolases
Aldolases are C-C bond forming enzymes that have become prominent tools for sustainable synthesis of complex synthons. However, enzymatic methods of fluorine incorporation into such compounds are lacking due to the rarity of fluorine in nature. Recently, the use of fluoropyruvate as a non-native ald...
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| 出版年: | Angew Chem Int Ed Engl |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7224411/ https://ncbi.nlm.nih.gov/pubmed/31240790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201906805 |
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