Transcription factor TAp73 and microRNA-449 complement each other to support multiciliogenesis

Motile cilia serve vital functions in development, homeostasis, and regeneration. We recently demonstrated that TAp73 is an essential transcriptional regulator of respiratory multiciliogenesis. Here, we show that TAp73 is expressed in multiciliated cells (MCCs) of diverse tissues. Analysis of TAp73...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Wildung, Merit, Esser, Tilman Uli, Grausam, Katie Baker, Wiedwald, Cornelia, Volceanov-Hahn, Larisa, Riedel, Dietmar, Beuermann, Sabine, Li, Li, Zylla, Jessica, Guenther, Ann-Kathrin, Wienken, Magdalena, Ercetin, Evrim, Han, Zhiyuan, Bremmer, Felix, Shomroni, Orr, Andreas, Stefan, Zhao, Haotian, Lizé, Muriel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224178/
https://ncbi.nlm.nih.gov/pubmed/31068677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0332-7
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