miR-34/449 control apical actin network formation during multiciliogenesis through small GTPase pathways

Vertebrate multiciliated cells (MCCs) contribute to fluid propulsion in several biological processes. We previously showed that microRNAs of the miR-34/449 family trigger MCC differentiation by repressing cell cycle genes and the Notch pathway. Here, using human and Xenopus MCCs, we show that beyond...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Chevalier, Benoît, Adamiok, Anna, Mercey, Olivier, Revinski, Diego R., Zaragosi, Laure-Emmanuelle, Pasini, Andrea, Kodjabachian, Laurent, Barbry, Pascal, Marcet, Brice
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Pub. Group 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595761/
https://ncbi.nlm.nih.gov/pubmed/26381333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9386
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