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miR-34/449 control apical actin network formation during multiciliogenesis through small GTPase pathways

Vertebrate multiciliated cells (MCCs) contribute to fluid propulsion in several biological processes. We previously showed that microRNAs of the miR-34/449 family trigger MCC differentiation by repressing cell cycle genes and the Notch pathway. Here, using human and Xenopus MCCs, we show that beyond...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chevalier, Benoît, Adamiok, Anna, Mercey, Olivier, Revinski, Diego R., Zaragosi, Laure-Emmanuelle, Pasini, Andrea, Kodjabachian, Laurent, Barbry, Pascal, Marcet, Brice
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595761/
https://ncbi.nlm.nih.gov/pubmed/26381333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9386
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