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miR-34/449 control apical actin network formation during multiciliogenesis through small GTPase pathways

Vertebrate multiciliated cells (MCCs) contribute to fluid propulsion in several biological processes. We previously showed that microRNAs of the miR-34/449 family trigger MCC differentiation by repressing cell cycle genes and the Notch pathway. Here, using human and Xenopus MCCs, we show that beyond...

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Publicat a:Nat Commun
Autors principals: Chevalier, Benoît, Adamiok, Anna, Mercey, Olivier, Revinski, Diego R., Zaragosi, Laure-Emmanuelle, Pasini, Andrea, Kodjabachian, Laurent, Barbry, Pascal, Marcet, Brice
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595761/
https://ncbi.nlm.nih.gov/pubmed/26381333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9386
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