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Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth
A goal of HIV vaccine development is to elicit antibodies with neutralizing breadth. Broadly neutralizing antibodies (bNAbs) to HIV often have unusual sequences with long heavy-chain complementarity-determining region loops, high somatic mutation rates and polyreactivity. A subset of HIV-infected in...
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| Publicat a: | Nat Immunol |
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| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group US
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7223457/ https://ncbi.nlm.nih.gov/pubmed/31959979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0581-0 |
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