Shaping of infant B cell receptor repertoires by environmental factors and infectious disease

Antigenic exposures at epithelial sites in infancy and early childhood are thought to influence the maturation of humoral immunity and modulate the risk of developing IgE-mediated allergic disease. How different kinds of environmental exposures influence B cell isotype switching to IgE, IgG, or IgA,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Transl Med
Main Authors: Nielsen, Sandra C. A., Roskin, Krishna M., Jackson, Katherine J. L., Joshi, Shilpa A., Nejad, Parastu, Lee, Ji-Yeun, Wagar, Lisa E., Pham, Tho D., Hoh, Ramona A., Nguyen, Khoa D., Tsunemoto, Hannah Y., Patel, Sonal B., Tibshirani, Robert, Ley, Catherine, Davis, Mark M., Parsonnet, Julie, Boyd, Scott D.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733608/
https://ncbi.nlm.nih.gov/pubmed/30814336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat2004
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