Shaping of infant B cell receptor repertoires by environmental factors and infectious disease

Antigenic exposures at epithelial sites in infancy and early childhood are thought to influence the maturation of humoral immunity and modulate the risk of developing IgE-mediated allergic disease. How different kinds of environmental exposures influence B cell isotype switching to IgE, IgG, or IgA,...

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Foilsithe in:Sci Transl Med
Main Authors: Nielsen, Sandra C. A., Roskin, Krishna M., Jackson, Katherine J. L., Joshi, Shilpa A., Nejad, Parastu, Lee, Ji-Yeun, Wagar, Lisa E., Pham, Tho D., Hoh, Ramona A., Nguyen, Khoa D., Tsunemoto, Hannah Y., Patel, Sonal B., Tibshirani, Robert, Ley, Catherine, Davis, Mark M., Parsonnet, Julie, Boyd, Scott D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733608/
https://ncbi.nlm.nih.gov/pubmed/30814336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat2004
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