Shaping of infant B cell receptor repertoires by environmental factors and infectious disease

Antigenic exposures at epithelial sites in infancy and early childhood are thought to influence the maturation of humoral immunity and modulate the risk of developing IgE-mediated allergic disease. How different kinds of environmental exposures influence B cell isotype switching to IgE, IgG, or IgA,...

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Библиографические подробности
Опубликовано в: :Sci Transl Med
Главные авторы: Nielsen, Sandra C. A., Roskin, Krishna M., Jackson, Katherine J. L., Joshi, Shilpa A., Nejad, Parastu, Lee, Ji-Yeun, Wagar, Lisa E., Pham, Tho D., Hoh, Ramona A., Nguyen, Khoa D., Tsunemoto, Hannah Y., Patel, Sonal B., Tibshirani, Robert, Ley, Catherine, Davis, Mark M., Parsonnet, Julie, Boyd, Scott D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733608/
https://ncbi.nlm.nih.gov/pubmed/30814336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat2004
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