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Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes

BACKGROUND: Cardiotoxicity, characterized by severe cardiac dysfunction, is a major problem in patients treated with different classes of anticancer drugs. Development of predictable human-based models and assays for drug screening are crucial for preventing potential drug-induced adverse effects. C...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Cao, Lu, der Meer, Andries D. van, Verbeek, Fons J., Passier, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222481/
https://ncbi.nlm.nih.gov/pubmed/32408861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3466-1
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