Histone deacetylase 9 promoter hypomethylation associated with adipocyte dysfunction is a statin-related metabolic effect

BACKGROUND: Adipogenesis, the process whereby preadipocytes differentiate into mature adipocytes, is crucial for maintaining metabolic homeostasis. Cholesterol-lowering statins increase type 2 diabetes (T2D) risk possibly by affecting adipogenesis and insulin resistance but the (epi)genetic mechanis...

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Bibliografiske detaljer
Udgivet i:Clin Epigenetics
Main Authors: Khamis, Amna, Boutry, Raphael, Canouil, Mickaël, Mathew, Sumi, Lobbens, Stephane, Crouch, Hutokshi, Andrew, Toby, Abderrahmani, Amar, Tamanini, Filippo, Froguel, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222462/
https://ncbi.nlm.nih.gov/pubmed/32410704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00858-w
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