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Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes

OBJECTIVE: Genome wide association studies (GWAS) for type 2 diabetes (T2D) have identified genetic loci that often localise in non-coding regions of the genome, suggesting gene regulation effects. We combined genetic and transcriptomic analysis from human islets obtained from brain-dead organ donor...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Khamis, Amna, Canouil, Mickaël, Siddiq, Afshan, Crouch, Hutokshi, Falchi, Mario, Bulow, Manon von, Ehehalt, Florian, Marselli, Lorella, Distler, Marius, Richter, Daniela, Weitz, Jürgen, Bokvist, Krister, Xenarios, Ioannis, Thorens, Bernard, Schulte, Anke M., Ibberson, Mark, Bonnefond, Amelie, Marchetti, Piero, Solimena, Michele, Froguel, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531807/
https://ncbi.nlm.nih.gov/pubmed/30956117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.03.004
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