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Potential Benefits of Nrf2/Keap1 Targeting in Pancreatic Islet Cell Transplantation

Permanent pancreatic islet cell destruction occurs in type 1 diabetes mellitus (T1DM) through the infiltration of inflammatory cells and cytokines. Loss of β-cell integrity secondary to oxidation leads to an inability to appropriately synthesize and secrete insulin. Allogenic islet cell transplantat...

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Publicat a:Antioxidants (Basel)
Autors principals: Jarrin Lopez, Alberto, Lau, Hien, Li, Shiri, Ichii, Hirohito
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222398/
https://ncbi.nlm.nih.gov/pubmed/32316115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9040321
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