MicroRNA-421-3p-abundant small extracellular vesicles derived from M2 bone marrow-derived macrophages attenuate apoptosis and promote motor function recovery via inhibition of mTOR in spinal cord injury

BACKGROUND: Spinal cord injury (SCI) has a very disabling central nervous system impact but currently lacks effective treatment. Bone marrow-derived macrophages (BMDMs) are recruited to the injured area after SCI and participate in the regulation of functional recovery with microglia. Previous studi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Nanobiotechnology
Hlavní autoři: Wang, Jiaxing, Rong, Yuluo, Ji, Chengyue, Lv, Chengtang, Jiang, Dongdong, Ge, Xuhui, Gong, Fangyi, Tang, Pengyu, Cai, Weihua, Liu, Wei, Fan, Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222346/
https://ncbi.nlm.nih.gov/pubmed/32404105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00630-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky