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Familial dysalbuminaemic hyperthyroxinaemia interferes with current free thyroid hormone immunoassay methods

OBJECTIVE: Familial dysalbuminaemic hyperthyroxinaemia (FDH), most commonly due to an Arginine to Histidine mutation at residue 218 (R218H) in the albumin gene, causes artefactual elevation of free thyroid hormones in euthyroid individuals. We have evaluated the susceptibility of most current free t...

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Detalhes bibliográficos
Publicado no:Eur J Endocrinol
Main Authors: Khoo, Serena, Lyons, Greta, McGowan, Anne, Gurnell, Mark, Oddy, Susan, Visser, W Edward, van den Berg, Sjoerd, Halsall, David, Taylor, Kevin, Chatterjee, Krishna, Moran, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222281/
https://ncbi.nlm.nih.gov/pubmed/32213658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-19-1021
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