Familial dysalbuminaemic hyperthyroxinaemia interferes with current free thyroid hormone immunoassay methods

OBJECTIVE: Familial dysalbuminaemic hyperthyroxinaemia (FDH), most commonly due to an Arginine to Histidine mutation at residue 218 (R218H) in the albumin gene, causes artefactual elevation of free thyroid hormones in euthyroid individuals. We have evaluated the susceptibility of most current free t...

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Dades bibliogràfiques
Publicat a:Eur J Endocrinol
Autors principals: Khoo, Serena, Lyons, Greta, McGowan, Anne, Gurnell, Mark, Oddy, Susan, Visser, W Edward, van den Berg, Sjoerd, Halsall, David, Taylor, Kevin, Chatterjee, Krishna, Moran, Carla
Format: Artigo
Idioma:Inglês
Publicat: Bioscientifica Ltd 2020
Matèries:
Clinical Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222281/
https://ncbi.nlm.nih.gov/pubmed/32213658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-19-1021
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