CXCR4 and JUNB double-positive disseminated tumor cells are detected frequently in breast cancer patients at primary diagnosis

BACKGROUND: The chemokine receptor CXCR4 and the transcription factor JUNB, expressed on a variety of tumor cells, seem to play an important role in the metastatic process. Since disseminated tumor cells (DTCs) in the bone marrow (BM) have been associated with worse outcomes, we evaluated the expres...

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Vydáno v:Ther Adv Med Oncol
Hlavní autoři: Kallergi, Galatea, Hoffmann, Oliver, Bittner, Ann-Kathrin, Papadimitriou, Lina, Katsarou, Spyridoula D., Zacharopoulou, Nefeli, Zervakis, Michalis, Sfakianakis, Stelios, Stournaras, Christos, Georgoulias, Vassilis, Kimmig, Rainer, Kasimir-Bauer, Sabine
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222234/
https://ncbi.nlm.nih.gov/pubmed/32426042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835919895754
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