Phosphorylated EGFR and PI3K/Akt signaling kinases are expressed in circulating tumor cells of breast cancer patients

INTRODUCTION: The phosphoinositide-3 kinase (PI3K)/Akt pathway, operating downstream of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor (HER)2, is implicated in cell migration and survival. EGFR and HER2 are expressed in circulating tumor cells, but the activation...

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Bibliografske podrobnosti
Main Authors: Kallergi, Galatea, Agelaki, Sofia, Kalykaki, Antonia, Stournaras, Christos, Mavroudis, Dimitris, Georgoulias, Vassilis
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614515/
https://ncbi.nlm.nih.gov/pubmed/18822183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2149
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