5-Oxo-hexahydroquinoline Derivatives and Their Tetrahydroquinoline Counterparts as Multidrug Resistance Reversal Agents

Cancer is a leading cause of death worldwide. Multidrug resistance (MDR) is a main reason of chemotherapy failure in many patients and is often related to overexpression of ATP-binding cassette (ABC) transporters, including P-glycoprotein (P-gp/ABCB1). Agents that are capable of modulation of the ac...

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Publicado en:Molecules
Autores principales: Shahraki, Omolbanin, Khoshneviszadeh, Mehdi, Dehghani, Mojtaba, Mohabbati, Maryam, Tavakkoli, Marjan, Saso, Luciano, Edraki, Najmeh, Firuzi, Omidreza
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221826/
https://ncbi.nlm.nih.gov/pubmed/32316291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25081839
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