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Iron protects childhood acute lymphoblastic leukemia cells from methotrexate cytotoxicity

Drug resistance is a fundamental clinical concern in pediatric acute lymphoblastic leukemia (pALL), and methotrexate (MTX) is an essential chemotherapy drug administered for the treatment. In the current study, the effect of iron in response to methotrexate and its underlying mechanisms were investi...

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Publicat a:Cancer Med
Autors principals: Abedi, Marjan, Rahgozar, Soheila, Esmaeili, Abolghasem
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221302/
https://ncbi.nlm.nih.gov/pubmed/32176452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2982
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