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Iron protects childhood acute lymphoblastic leukemia cells from methotrexate cytotoxicity

Drug resistance is a fundamental clinical concern in pediatric acute lymphoblastic leukemia (pALL), and methotrexate (MTX) is an essential chemotherapy drug administered for the treatment. In the current study, the effect of iron in response to methotrexate and its underlying mechanisms were investi...

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Détails bibliographiques
Publié dans:Cancer Med
Auteurs principaux: Abedi, Marjan, Rahgozar, Soheila, Esmaeili, Abolghasem
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221302/
https://ncbi.nlm.nih.gov/pubmed/32176452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2982
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