ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure

Cystic fibrosis patients suffer from a progressive, often fatal lung disease, which is based on a complex interplay between chronic infections, locally accumulating immune cells and pulmonary tissue remodeling. Although group-2 innate lymphoid cells (ILC2s) act as crucial initiators of lung inflamma...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Schulz-Kuhnt, Anja, Greif, Vicky, Hildner, Kai, Knipfer, Lisa, Döbrönti, Michael, Zirlik, Sabine, Fuchs, Florian, Atreya, Raja, Zundler, Sebastian, López-Posadas, Rocío, Neufert, Clemens, Ramming, Andreas, Kiefer, Alexander, Grüneboom, Anika, Strasser, Erwin, Wirtz, Stefan, Neurath, Markus F., Atreya, Imke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221160/
https://ncbi.nlm.nih.gov/pubmed/32457736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00691
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