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Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death

Cancer cells are characterized as highly proliferative at the expense of enhancement of metabolic rate. Consequently, cancer cells rely on antioxidant defenses to overcome the associated increased production of reactive oxygen species (ROS). The reliance of tumor metabolism on amino acids, especiall...

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Vydáno v:Front Oncol
Hlavní autoři: Daher, Boutaina, Vučetić, Milica, Pouysségur, Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221143/
https://ncbi.nlm.nih.gov/pubmed/32457843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00723
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