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Small Molecule Inhibitors of CRM1
The transport through the nuclear pore complex is used by cancer cells to evade tumor-suppressive mechanisms. Several tumor-suppressors have been shown to be excluded from the cell nucleus in cancer cells by the nuclear export receptor CRM1 and abnormal expression of CRM1 is oncogenic. Inhibition of...
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| Publié dans: | Front Pharmacol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7221118/ https://ncbi.nlm.nih.gov/pubmed/32574233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00625 |
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