Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease

Huntington disease (HD) is an inherited late-onset neurological disorder characterized by progressive neuronal loss and disruption of cortical and basal ganglia circuits. Cell replacement using human embryonic stem cells may offer the opportunity to repair the damaged circuits and significantly amel...

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Pubblicato in:Stem Cell Reports
Autori principali: Besusso, Dario, Schellino, Roberta, Boido, Marina, Belloli, Sara, Parolisi, Roberta, Conforti, Paola, Faedo, Andrea, Cernigoj, Manuel, Campus, Ilaria, Laporta, Angela, Bocchi, Vittoria Dickinson, Murtaj, Valentina, Parmar, Malin, Spaiardi, Paolo, Talpo, Francesca, Maniezzi, Claudia, Toselli, Mauro Giuseppe, Biella, Gerardo, Moresco, Rosa Maria, Vercelli, Alessandro, Buffo, Annalisa, Cattaneo, Elena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220987/
https://ncbi.nlm.nih.gov/pubmed/32302555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.03.018
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