Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma

A Rho GTPase-activating protein (RhoGAP), deleted in liver cancer 1 (DLC1), is known to function as a tumor suppressor in various cancer types; however, whether DLC1 is a tumor-suppressor gene or an oncogene in melanoma remains to be clarified. Here we revealed that high DLC1 expression was detected...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Yang, Xintao, Hu, Feng, Liu, Jessica Aijia, Yu, Shan, Cheung, May Pui Lai, Liu, Xuelai, Ng, Irene Oi-Lin, Guan, Xin-Yuan, Wong, Kelvin K. W., Sharma, Rakesh, Lung, Hong Lok, Jiao, Yufei, Lee, Leo Tsz On, Cheung, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220869/
https://ncbi.nlm.nih.gov/pubmed/32214200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1274-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados