SNP rs17079281 decreases lung cancer risk through creating an YY1-binding site to suppress DCBLD1 expression

Genome-wide association studies (GWAS) have identified numerous genetic variants that are associated with lung cancer risk, but the biological mechanisms underlying these associations remain largely unknown. Here we investigated the functional relevance of a genetic region in 6q22.2 which was identi...

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Vydáno v:Oncogene
Hlavní autoři: Wang, Yu, Ma, Rongna, Liu, Ben, Kong, Jinyu, Lin, Hongyan, Yu, Xiao, Wang, Ruoyang, Li, Lei, Gao, Ming, Zhou, Baosen, Mohan, Man, Yu, Herbert, Hou, Zhaoyuan, Shen, Hongbin, Qian, Biyun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220863/
https://ncbi.nlm.nih.gov/pubmed/32231272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1278-4
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